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CSU Animal Cancer Center Clinical Trial

Patient Disease:
Canine Glioma

Study Name:
Canine Brain Tumor Vaccine Clinical Trial

Purpose of the study:

  • Evaluation of preliminary tumor response to vaccine that targets cancer stem cells as well as vaccine tolerability

Primary Eligibility Criteria:

  • Dogs with glioma type tumors based on MRI characteristics
  • Patients must still be in overall good health and stable condition
  • Not dependent on prednisone to control clinical signs
  • Seizures (if occurring) must be controlled with anti-convulsant medication
  • Measureable disease present and visible on MRI

Study Protocol:

  • Pre-enrollment screening: physical/neurological exam, blood tests, MRI of the brain
  • Vaccination, physical exam, study blood sampling once a week for 4 weeks; then every other week for 4 more vaccines (total of 8 vaccinations).
  • Follow up MRI scans at week 4, 12 and 24

Owner Responsibilities:

  • Costs of initial screening tests (consultation/physical exam, blood and urine tests) and exam costs at each recheck ($15 x 10 visits = $150)
  • Make and keep all appointments associated with the study

Financial Incentives:

  • Owners will receive the vaccinations and blood evaluation for anti-tumor response at no charge
  • Costs of MRI scans, pre-anesthetic bloodwork for MRIs, and daytime outpatient hospitalization fees for day of MRI scans will be covered by study
  • Up to $500 is available for treatment of vaccine-related adverse events

If you have further questions about any of our clinical trials, Please either login or sign up to submit a consulting form. Your consult will then be directed to an appropriate oncology clinician. Requests are typically returned within 5 business days